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In humans, the relapse
into dependence after the firste drink is accelerated by
700 times.
In rats inhaling ethanol between 15 to 23 mg per
litre of air during 21 days, a withdrawal is observed.
After 14 days of abstinence, 13 days of inhalation
were enough to induce the withdrawal.
A third inhalation was followed by a lethal withdrawal.
- Aufrère
G, Beaugé F, Besançon F:
Faster physical dependence acquisition following reiterative
chronic ethanol by inhalation in rats.
Poster, Congress of International Society for Biomedical
Research on Alcoholism (ISBRA), 1996. Summary in Alcoholism
Clin Exp Res 1996; 20 (Suppl April): 21 A (423).
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